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Comparing Receptor Selectivity, Half-Life, and Feedback Regulation The bottom line: IGF-1 LR3 delivers predictable, systemic anabolism in models where pituitary function is impaired or irrelevant to the research question

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The majority of reports of nausea, vomiting and/or diarrhea occurred during dose escalation

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Semaglutide was well tolerated by most people, although approximately half in each treatment group reported GI side effects (Supplementary Table S3)