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At 6 h after infection, there were 607 and 448 genes upregulated and downregulated, respectively, by SARS-CoV-2 infection (Supplementary Tables 1, 2)
Phase 2b human trial data available (obesity)
According to the results from in vitro and in vivo studies, tanshinone IIA pretreatment protects the liver from APAP-induced liver injury by activating Nrf2 and increasing the mRNA and protein levels of the Nrf2 target genes glutamate-cysteine ligase catalytic subunit (GCLC), NQO1, and HO-1 (Wang et al., 2016)
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