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Common reasons extrapolated from review of the medical records included ongoing treatment with VPA and reported symptoms suggestive of HA, given that the majority of the patients were on treatment with VPA (66% of both HA and non-HA groups) and 37% reported symptoms at the time of testing

It also activates molecular chaperones to prevent protein misfolding and aggregate formation [89]

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[19] SAM plays a critical function in epigenetic control by encouraging DNA methylation