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Tirzepatide SURMOUNT trials: raising the bar Then came the SURMOUNT trials

- - - In a study of 460,000+ adults on GLP-1s (mostly with T2D): 13% developed nutritional deficiencies in 6 months 22% within 12 months Vitamin D deficiency was most common (13.6%) 3% experienced muscle loss Patients who saw a dietitian were more likely to have deficiencies identifiednot because dietitians caused harm, but because they actually looked

JAMA Intern Med 185, 778 (2025)

Growth hormone receptor expression