Clinical studies have shown GLP-1 receptor agonists may reduce high-sensitivity C-reactive protein (hs-CRP), tumour necrosis factor-alpha (TNF-), interleukin-6 (IL-6), and interleukin-1 beta (IL-1)
Patients already doing resistance training, or planning to begin, benefit additionally from photobiomodulations muscle-recovery support, which helps sustain training consistency under caloric restriction
The effects of GLP-1 and dual agonists on lipid metabolism also provide a more complete treatment plan for metabolic diseases
Because insulin resistance in PCOS is a whole-body phenomenon expressed most strongly in skeletal muscle, liver, and adipose tissue, and retatrutides three signals converge on exactly those tissues indirectly, by driving large reductions in body weight and ectopic (especially hepatic) fat, and possibly directly, through incretin effects on the pancreatic islet and on adipose biology
Combine resistance training (23/week) with regular aerobic activity to preserve muscle and enhance metabolic adaptations
