tirzepatide versus semaglutide once weekly compared to SC #semaglutide for T2DM : a network meta-analysis 📍📍All tirzepatide doses outperformed in HbA1c & weight reduction. 📍📍Both drugs increased GI side effects, tirzepatide 15 mg had highest Tirzepatide versus Semaglutide Once Weekly

You get approved for a ton of indications that all have large populations

The Promise of Repurposed Drugs However, the GLP-1 saga turns out, the fact that these drugs have popped up seemingly out of nowhere, and have generated such excitement, highlights the potential existing in the huge repurposed drug (drugs used in another condition than for which they are approved) market for these diseases

In the context of triple agonism, the hyperglycemic effect of GCGR agonism is effectively offset by the robust glucose-lowering effects of GLP-1R and GIPR co-activation

Journal of Medicinal Chemistry, 67 (1), 180198.

But what about OTC supplements