Adv Psychosom Med 34:6177 Cordero MD, de Miguel M, Carmona-Lpez I, Bonal P, Campa F, Moreno-Fernndez AM (2010) Oxidative stress and mitochondrial dysfunction in fibromyalgia
These reactive aldehydes further disrupt mitochondrial function, activate pro-inflammatory pathways (e.g., NF-B), and sensitize nociceptive neurons, contributing to neuroinflammation, neuronal dysfunction in FM ( Mitochondrial dysfunction in FM is evident from reduced electron transport chain (ETC) activity, lower oxygen consumption in muscle biopsies, and diminished bioenergetic reserve (6)
Inject at the center of the triangle
[DOI] [PMC free article] [PubMed] [Google Scholar] Arunkumar A
In addition, the development of immunopeptidome analysis should provide successful targets and open the way to a new generation of senolytic treatments