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Among the patients who develop NASH, 1020% will progress to higher-grade fibrosis and approximately 5% will develop overt cirrhosis (1) ( Figure 1 Triglycerides (TG) accumulation is likely one of the first steps in the pathophysiology of NAFLD as a result of an impaired free fatty acid (FFA) metabolism in the liver (Figure 2)

Orgaard A, Holst JJ (2017) The role of somatostatin in GLP-1-induced inhibition of glucagon secretion in mice

Athauda and colleagues 26 reported that exenatide 2 mg once weekly had numerically greater improvements in individual domains assessing mood/depression across all observer rated outcome measures including the mood/apathy domain of the Non-Motor Symptoms Scale in Parkinson Disease

[DOI] [PubMed] [Google Scholar] 66.The cardiovascular effects of GLP-1 receptor agonists

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