Glucagon-like peptide-1, or GLP-1, is a naturally occurring intestinal hormone involved in glucose regulation, appetite, and digestion
Raw crucifers or sprouts yield higher sulforaphane exposure than myrosinase-free supplements, although gut microbial -thioglucosidases can partially compensate for enzyme loss
Moreover, it is required for the transport and metabolism of fats and cholesterol, which is important for the healthy support of the endocrine, cardiovascular, and hepatic systems
This suggests that the process of GSH-mediated ROS detoxification has important influence on the level of [ROS] during retinal development and degeneration
It is also important to point out that unlike Grx1, Grx2 complexes iron (Fe), which is required to modulate its activity (Johansson et al., 2004