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In one study, the target dose was 2.4 mg once weekly

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Melatonin has previously shown various pharmacological effects, including the ability to reduce oxidative stress, regulate circadian rhythms, prevent apoptosis, and reduce inflammation (Lendahl and Siebel, 2017

Injection site reactions produce localized redness, swelling, or mild bruising that resolves within 24-48 hours and remains confined to the puncture area