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For example, in macrophages, the activation of NF-B in response to LPS stimulation leads to the production of proinflammatory cytokines e.g., TNF- and interleukin-6 (IL-6), which are important for the initiation and regulation of the immune response [130]

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In one 12-week study, 124 women with at least one facial dark spot were given L-glutathione or L-cysteine, or both (or placebo), each day

Type-2 cytokines are implicated in humoral immune responses (antibody synthesis) whereas type-1 are generally more involved in cellular immunity

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