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1 Key results for oral semaglutide 14 mg: HbA1c reduction: -1.5% (vs -0.1% with placebo) 80% achieved HbA1c below 7.0% (vs 34% with placebo) Weight loss: 2.3-2.6 kg more than placebo Injectable semaglutide: the SUSTAIN programme Across the SUSTAIN trials in type 2 diabetes: Semaglutide 0.5 mg: HbA1c reduction of approximately -1.5%, weight loss of 3-5 kg Semaglutide 1 mg: HbA1c reduction of approximately -1.5% to -1.8%, weight loss of 4.5-6.5 kg What explains the difference

Semaglutide is a synthetic glucagon-like peptide-1 receptor agonist (GLP-1 RA) developed to overcome the pharmacokinetic limitations of native GLP-1

Men with asthenospermia have less than 40% sperm motility or less than 32% progressive motility