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This recent study published in Springer Nature shows that losing weight using GLP-1 alone doesn't automatically restore vascular health The findings are a stark reminder that weight reduction alone is not a proxy for #CardiovascularHealth: The Medication Flaw: GLP-1 on its own demonstrated no statistical improvements in arterial wall thickness or systemic inflammation The Movement Requirement: Regular physical activity - with or without the medication - was the single essential driver behind reduced arterial thickness and lowered pro-inflammatory cytokines The Synergy: Combining exercise with GLP-1 drug maximized vascular health and protection Operational takeaway for preventative clinics and health assessment providers: If your longevity or #HealthScreening programs only measure the scale, you are missing the internal reality
Marlon Pragnell, ADAs vice president of research and science
The truth is, we dont fully know yet
The differences in cardiovascular outcomes observed between trials of GLP-1 receptor agonists may relate to variations in the design and populations of the trials, but could also be the result of the different characteristics of the GLP-1 receptor agonists themselves (39,40)
In fact, most people don't
