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Dual agonism with GLP-1 and amylin As WL with GLP-1 RA and amylin analogues results both from distinct and overlapping pathways, a combination of these entero-pancreatic hormones may induce a synergistic WL effect [84]

GLP-1 drugs slow gastric emptying, which can alter absorption of oral supplements

While semaglutide has not been studied in a dedicated OSA trial of this scale, the weight loss it produces likely offers similar benefits, since the primary mechanism is fat reduction around the airway and abdomen

While GLP-1s clearly are effective for weight loss, experts may be concerned if their patients do not make other lifestyle changes, for example, changing their diet or being more active

There were no significant differences in TNF-, IL-2, and IL-6 levels among the three groups