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(108) found that long-term fasting-mimicking diet (FMD) cycles reduced hippocampal A load and tau hyperphosphorylation in E4FAD and 3xTg AD mouse models, enhanced neurogenesis, reduced the number of microglia, and decreased the expression of neuroinflammatory genes, including the superoxide-producing NADPH oxidase (Nox2)

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Our regression analysis also suggests that Glu/H 2 O decreases with age in children and adults, consistent with the age decrease of Glx/Cr reported by Gao et al., 43 although their results were derived from frontal and parietal regions