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GLP-1 activates a seven transmembrane G protein coupled receptor, GLP-1R

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Overview 5-Amino-1MQ is widely studied in research focused on metabolic signaling, cellular energy balance, and body composition related pathways

Cell culture Baby hamster kidney (BHK) cells stably over-expressing human, cynomolgus, rat, mouse and pig GLP-1 receptor, human glucagon receptor, human GIP receptor, human GLP-2 receptor or co-expressing hGLP-1R and cAMP response element (CRE) coupled to firefly luciferase (CRE luciferase) were generated at Novo Nordisk A/S