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When to Pause Treatment and How Genetics Guide Your Dosing Stop taking your GLP-1 medication and contact your provider immediately if you experience severe vomiting that prevents you from keeping down food or fluids, signs of pancreatitis (severe upper abdominal pain radiating to the back), or persistent constipation lasting more than 3 days despite fiber and hydration

To determine which genes drive the differences in transcriptional landscape among the various subclusters, we focused on functionally related genes that exhibited high differential expression between each subcluster within individual endocrine cell populations as well as other known and cell marker genes

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