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Our group recently described that a genetic disruption of the xCT subunit using CRISPR-Cas9 inhibits protein synthesis and proliferation in vitro ( 14 C-cystine transport assay in xCT knockout (xCT-KO) cells revealed this transporter as unique and indispensible for cystine uptake, as a complete abolishment of cystine transport has been observed

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Statistical significance is calculated by one-way ANOVA followed by a correction for multiple comparisons as indicated in Section Materials and Methods. ANOVA, analysis of variance

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The most common methods of BPC 157 administration include: Oral liquid solution Nasal spray Oral capsule And local injection