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We acknowledged this as a limitation of the study and are aware that it may affect the interpretation of the results

That suggests the amylin and GLP-1 pathways create a synergistic interaction, not just a combined one

Learn more: Lilly Medical Globals Post New Results from ATTAIN-1 An Oral Small Molecule GLP-1 Receptor Agonist for Obesity Treatment

[53] While sertraline does not typically cause significant sedation as a monotherapy, the combination with alcohol can impair cognitive function and motor coordination to a greater degree than either substance alone

Fat compartments around the eyes are sensitive to metabolic shifts