Curcumin I is considered a principal curcuminoid
However, oral glutathione is a bit controversial in the medical community
It is to restore immune tolerance, the state where the immune system correctly identifies self-tissue as friendly and stops attacking it
In physical dependence assay (isoniazid challenge assessed at 6, 14, 42 and 72 h after conditioning medication), when compared to diazepam non-conditioned healthy mice, in diazepam conditioned mice residual anticonvulsive activity was not present already at the earliest post-conditioning interval (i.e., not different latency to isoniazid-convulsions), whereas shorter preconvulsive latencies (as physical dependence/withdrawal hallmark) were noted in diazepam conditioned mice following isoniazid challenge at 42 h and at 72 h after end of conditioning treatment
Sikiric, P., Boban Blagaic, A., Strbe, S., Beketic Oreskovic, L., Oreskovic, I., Suncana Sikiric, S., Staresinic, M., Sever, M., Kokot, A., Jurjevic, I., Matek, D., Coric, L., Krezic, I., Tvrdeic, A., Lueti, K., Batelja Vuleti, L., Pavic, P., Mestrovic, T., Sjekavica, I., & Skrtic, A