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Patients who experience gastrointestinal side effects may see reduced appetite and faster initial weight loss, while others may experience slower early response and plateau sooner

Berthoud HR, Patterson LM, Neumann F, Neuhuber WL

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But the effects may not be limited to people with an addiction

Fasting amplifies this effectplasma free fatty acid concentrations rise 2.5 higher when AOD-9604 is injected after an 812 hour fast versus post-prandial states where insulin blunts HSL activation