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Protective role of Kupffer cells in acetaminophen-induced hepatic injury in mice

117 In females with mild-to-moderate chronic constipation, 500 mg magnesium oxide taken three times daily for 28 days significantly improved the frequency of spontaneous bowel movements (SBM), colon transit time, and Bristol stool consistency scores compared with placebo

As testing becomes more accessible and affordable, precision approaches will likely replace the current one-size-fits-most protocol paradigm

Analysis of over 11,000 participants in the SUSTAIN and PIONEER trials revealed that gastrointestinal disorders were the predominant adverse effects, occurring in approximately 39-42% of semaglutide users compared to 22-25% of those receiving comparators

doi: 10.1210/jc.2013-2376