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Efficiency of mRNA depletion was assessed 72 h post-transfection using qPCR or western blot in the case of ACSL1 (Cell Signaling, Antibody #4047, used 1:1000), GPX4 (Abcam, [EPNCIR144], ab125066, used 1:1000), DGAT1 (Abcam, [EPR13430-4] - N-terminal ab181180, used 1:5000), DGAT2 (ThermoFisher Scientific, PA5-103785, used 1:1000), and ATGL (Cell Signaling, Antibody #2138, used 1:1000)

& Cheresh, D.A

Oxidized Low-Density Lipoprotein Contributes to Atherogenesis via Co-Activation of Macrophages and Mast Cells. PloS One, vol

(11) Smith TJ

Anabolic Signaling in Preclinical Models In preclinical models, activation of this pathway is associated with several downstream signaling events: increased protein synthesis via mTOR activation, stimulation of satellite cells that contribute to muscle fiber development, and inhibition of the FOXO pathway, which under normal conditions promotes protein breakdown