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Three key findings emerged from this study: (1) PRMT1 upregulation in injured TECs drives UBE2m methylation at R169, (2) methylated UBE2m promotes NEDD4 neddylation and subsequent PPAR ubiquitination, and (3) this pathway is clinically relevant in stone patients, correlating with renal function decline

Tolomeo, A.M., Carraro, A., Bakiu, R., Toppo, S., Garofalo, F., Pellegrino, D., Gerdol, M., Ferro, D., Place, S.P

doi: 105

With the right knowledge and approach, collagen supplementation can be an effective tool in managing the signs of aging and supporting the body's structural integrity

Minimizes the pores and improves the skin complexion