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Among these, 31,407 (54.2%) participants were classified as engaged and 26,568 (45.8%) participants as nonengaged at baseline (month 0)

Journal of Clinical Gastroenterology, 54 (5), 405414

Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia

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The glucagon component is thought to enhance thermogenesis the body's heat-generating metabolic processes potentially contributing to fat loss beyond what GLP-1 and GIP agonism alone can achieve