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A 30-year-old with no cancer history and no significant family history faces fundamentally different considerations than a 55-year-old with previous cancer or strong hereditary risk

Secondary mitochondrial dysfunction Acquired dysfunction may develop from oxidative stress, inflammation, nutrient deficiency, medication toxicity, toxic exposure, aging, metabolic disease, infection, poor sleep, inactivity or chronic illness

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Cardiac involvement in inflammatory bowel disease: role of acylcarnitine esters