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However, depending on how appetite, hydration, digestion, and food intake change over time, certain nutrients may become more difficult to maintain consistently through meals alone

But for some, the nausea is severe enough to force microdosing approaches or even complete discontinuation

There are also broader physiological concerns

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The FDA on Friday accepted Novo Nordisk s New Drug Application for an oral formulation of its widely popular obesity drug Wegovy for chronic weight management, bringing the Danish drugmaker one step closer to winning the first regulatory approval for a GLP-1 pill specifically for weight-loss