This test may help provide context for why a patient responds robustly to one medication versus another, or why side effects vary
Data showed that WT-Bcr-Abl-32D cells had very low levels of dNTPs as compared to those in T315I-Bcr-Abl-32D and untransformed 32D cells, with the most significant difference in dTTP pool (Fig
For gene expression analysis, cDNA was synthesized using the First Strand cDNA-Synthesis Kit with Random Hexamer Primers (K1612, Thermo Fisher Scientific) according to manufacturers instructions
Commonly reported side effects include: Gastrointestinal symptoms nausea, vomiting, diarrhoea, and constipation are the most frequently reported adverse effects, particularly during dose escalation
However, L-carnitine is the best choice in cases of heart disease and weight management