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Final Thoughts on Glutathione for Skin Health Glutathione is a fascinating molecule with important roles in your body's antioxidant defense system, detoxification pathways, and cellular health

it upregulates the expression of tight junction proteins (e.g., ZO-1 and occludin) in colon tissue, repairs the intestinal epithelial barrier, reduces serum FD4 (fluorescein isothiocyanatedextran) levels, decreases intestinal permeability, prevents bacterial and metabolite translocation, and lowers serum LPS levels

M.ParkD.et al (2020)

Further research indicates that GST can influence the MAPK pathway both through JNK and TRAF2 modulation

In this way, glutathione absorption levels can be as high as 80%