There is no strong evidence suggesting gender-specific risks, but safety data is limited for both men and women
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The Grading of Recommendation, Assessment, Development, and Evaluation (GRADE) tool was used to assess the certainty of the evidence for the two primary biochemical outcomesserum vitamin B12 concentration increase and homocysteine reductionacross all included studies, and separately for randomised controlled trials (RCTs) and observational studies
According to CDC.gov: Gloves are not required when administering vaccines unless the person administering the vaccine is likely to come into contact with potentially infectious body fluids or has open lesions on hands (Pinkbook | Vaccine Administration | Epidemiology of VPDs | CDC, 2015)
Your healthcare provider will monitor your response to treatment through full blood count, mean corpuscular volume (MCV), and reticulocyte response rather than serum B12 levels after injection therapy