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In this regard, over the past 20 years, several clinical trials demonstrated the benefits of Se therapy, especially intravenous bolus administration, on clinical outcomes in patients with a critical illness [18]
The combination of phenylbutyrate (PBA) and 1,25-dihydroxyvitamin D3 (1,25(OH) 2 D3) induces LL-37 expression in a lung epithelial cell line and enhances M.tb killing in human monocyte-derived macrophages through activation of autophagy and resolution of lung pathology [150]
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