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It's also important to remember that if you have Leber's disease, a specific type of B12 called cyanocobalamin could be harmful to your optic nerve

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By inhibiting NNMT, the body maintains higher NAD levels, which in turn activate SIRT1, a longevity-associated gene, which may improve mitochondrial activity, fat oxidation, insulin sensitivity, and by overall energy balance

Monitor Treatment : Evaluate the effectiveness of vitamin B12 supplementation or treatment for conditions causing deficiency