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Since the exact cause of IBS is not known and is likely multifactorial, involving aspects such as gut-brain interaction, microbiome composition, and genetic and environmental factors, treatments are aimed at managing symptoms rather than curing the condition

This conformational restriction prevents the peptide from adopting flexible substrate orientations that proteases require for efficient cleavage

That proactive mindset, planning ahead rather than reacting after the fact, is the single most useful shift I can encourage in anyone navigating significant weight change through this medication class, regardless of where they are in that journey today