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10,13 In contrast to SGLT-2 inhibitors, GLP-1RAs do not significantly prevent decreases in estimated glomerular filtration rate or increases in creatinine levels

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Therefore, in this review our aim is to bring all IGF-1 information regarding metabolism together with the objective of offering clear insight into the issuethis way clarifying how miss-regulation of the GH/IGF-1/insulin axis can lead to metabolic disorders such as MetS and diabetes

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