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Recent Developments In February 2026 , Pfizer announced positive Phase 2b trial results for its ultra-long-acting injectable GLP-1 (PF-08653944), demonstrating significant weight loss with monthly dosing

Appetite suppression may begin in 35 days, and measurable weight loss (610 lbs) often appears by weeks 24

Epithalon is a synthetic four-amino-acid peptide (alanine-glutamic acid-aspartic acid-glycine, or AEDG) modeled on epithalamin, a compound made by the pineal gland

NAEs were identified using SOC = nervous system disorders (SOC ID: 10,029,205) and primary SOC = Yes, encompassing 1075 PTs from MedDRA version 27.0