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Drug regimen simplicity is an important clinical consideration, particularly in patients receiving multiple medications for the treatment of T2DM and related comorbidities

The diet, which primarily consists of animal products like meat and fish, can also provide this substance in addition to what the body naturally produces

Paul and Brady also note that various single-nucleotide polymorphisms (SNPs) may influence the efficacy and bioavailability, but that at this time there is neither sufficient clinical research in this area nor are tests for these SNPs commercially available

For individuals who discontinued treatment, weight and cardiometabolic risk factors were assumed to revert to baseline levels within a year, followed by risk factorspecific temporal trends in subsequent years