This can lead to inflammation of the gallbladder ( cholecystitis ), which can cause intense pain in your abdomen, between your shoulder blade, or in your right shoulder
doi:10.1016/b978-0-12-571131-9.50017-7 184
Being a naturally occurring peptide does not imply that it is effective or safe. These are biologically active compounds, added Cutler
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The compound has very low oral bioavailability, with only a small percentage absorbed in the small intestine