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As an analogue of -MSH, PT-141 acts on the melanocortin receptors (MCRs), which are found predominantly in the skin and central nervous system and cause an increase in pigmentation by activating melanocytes

doi: 10.1186/s13229-021-00447-5 151 Zuiderwijk-SickE

This is exactly where a continuous glucose monitor (CGM) changes the game and why, in 2026, a growing wave of GLP-1 users are pairing their medication with a wearable glucose biosensor

Use BAC water (not sterile water) and proper aseptic technique to minimize contamination risk

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