Subcutaneous weekly semaglutide with automated insulin delivery in type 1 diabetes: a double-blind, randomized, crossover trial
Cocaine and amphetamines (stimulants) All animal studies retrieved for stimulants misuse involved exendin-4 among GLP-1RAs and highlighted a reduction of cocaine and amphetamines intake and end effects (for example, increased locomotor activity) via modulation of dopaminergic transmission in areas including the nucleus accumbens and the ventral tegmental area 91,92,93,94,96,97,98,99,100,101,102,103,105 , as well as modulation of inflammatory mechanisms 104
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Both GLP-1RA and SGLT-2 inhibitors were associated with the same lower risk (12%) as compared with placebo, and the same lower risk as compared with DPP-4 inhibitors (13%)
11, 2024 DALLAS, Nov