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In clinical trials studying Wegovy (2.4 mg), the average weight loss was 15%, respectively, when paired with diet and exercise (compared to 2.4% and 3.1% with diet and exercise alone)

Data were analysed using a 3-parameter logistic fit in Prism and assessed for differences in fitted parameters from the parental construct at 95% confidence intervals

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Cultured rat hepatocytes also had elevated activities of these enzymes, whereas cultured human hepatocytes did not