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The primary role of MLT is to carry out the different physiological mechanisms associated with circadian and seasonal rhythms in the human body

The most accurate way to present Epitalon is as a promising peptide compound with established research interest and evolving regulatory attention

In line with ICH standards, the present procedures were validated 37

Patients in the high-risk group exhibited down-regulated immune-effector pathways, elevated expression of the checkpoint molecules PD-L1 and LAG-3, and a trend toward an immune-evasive phenotype, suggesting potential resistance to immunotherapy

Ethics declarations Competing interests J.S., M.-D.Z