semaglutide and thc (Ozempic) May Help Reduce Cannabis Use GLP-1 boom nudges cannabis dispensaries

Eur J Pharm Sci 48:726734 Pieber TR, et al (2019) Efficacy and safety of oral semaglutide with flexible dose adjustment versus sitagliptin in type 2 diabetes (PIONEER 7): a multicentre, open-label, randomised, phase 3a trial

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Measurement of liver tissue level of malondialdehyde (MDA), glutathione, and superoxide dismutase) After preparing the tissue homogenate, the double-sandwich enzyme-linked immunoassay (ELISA) technique is used to measure MDA, GSH, and SOD concentration in the supernatant for each marker from MyBioSource, USA, using an automated ELISA reader (ELISA-humareder , Germany)

This is one possible mechanism behind the association between inflammation, chronic diseases such as cardiovascular and metabolic conditions, and mood and anxiety disorders

Smaga I, Bystrowska B, Gawliski D, Przegaliski E, Filip M