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Mitochondrial Peptide: MOTS-c MOTS-c is a mitochondrial-derived peptide that has emerged as a promising metabolic regulator

doi: 10.1016/j.fitote.2013.04.005 25 JeongH-JKooH-NNaH-JKimM-SHongS-HEomJ-Wet al

d , Oxygen consumption of primary mouse hepatocytes shown as the percentage of total respiration that is driven by the oxidation of indicated substrates (n=2 biologically independent samples/group)

Answer: No, they are sometimes combined with topical therapy to increase and quicken outcomes

However, despite these promising effects, reports regarding tBHQs genotoxicity (Eskandani et al., 2014), pro-oxidative behavior (Imhoff and Hansen, 2010), and potential carcinogenicity (Gharavi et al., 2007) diminished its therapeutic appeal