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In fact, even with a lack of intrinsic factor the transport molecule which is essential for the absorption of B12 the body can obtain enough vitamin B12 from oral doses via passive diffusion in the small intestine

There is no benefit to reaching target dose faster if cardiovascular side effects become limiting

These side effects typically occur at the start of treatment and when switching to a higher dosage but tend to improve with time

It's crucial to start with a lower dose and gradually increase it over time, closely monitoring for any side effects

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