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In the pig data, plasma IGF-1, IGFBP-3, and growth hormone were all reduced by LR3 infusion (Tomas et al., 1997)

Becher M, Talke IN, Krall L, Krmer U: Cross-species microarray transcript profiling reveals high constitutive expression of metal homeostasis genes in shoots of the zinc hyperaccumulator Arabidopsis halleri

These physiological effects are concentration-dependent, with low BPA concentrations often reported to be most effective 27,29

Further, some of IL-18 effects may be mediated by NCC (Wang et al., 2015