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237 For example, in a rat model of high-fat diet-induced pancreatitis, severely impaired autophagy and substantial accumulation of unfolded proteins were observed

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Therefore, the Biopharmaceutics Classification System (BCS) class of each drug is also included in Table 1 to provide a comprehensive perspective on how specific formulation designs address respective oral delivery barriers (e.g., poor aqueous solubility for BCS II/IV drugs, or low membrane permeability for BCS III biologics)

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Imaging Med