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Despite decades of research on inflammation in AH, clinical trials of anti-inflammatory therapies have largely failed to achieve meaningful improvements in patient outcomes

Colloid Interface Sci

The SURMOUNT-5 head to head trial confirmed this pattern

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Although there is vast research on regenerative medicine approaches for skin wound healing, including cellular and biomaterial-based strategies, most of them are focused on young rather than aged subjects and the impact of estrogen deficiency in the outcomes of such therapies is still largely unknown