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Smaller gauges (31-gauge) create even less tissue trauma and may reduce post-injection soreness, though they require slightly more pressure to penetrate skin

For some, this less frequent dosing makes the injection route more convenient

This process leads to endothelial cell death, neuroinflammation, and the breakdown of BBB

(2005) Exenatide pharmacokinetics/pharmacodynamics/safety (PubMed) Three years of liraglutide vs placebo for type 2 diabetes risk reduction and weight management (The Lancet) Janzen KM, Steuber TD, Nisly SA