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Importantly, disruption of sleepwake cycles using a jetlag model recapitulated the effect of Per1/2 deletion on gut microbiota rhythmicity and homeostasis (57), highlighting the bidirectional relationship between sleep and gut microbiota and the mediating role of circadian mechanisms

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Tachycardia can be classified into different types based on where it originates in the heart: Atrial tachycardia: Starts in the atria, the upper chambers of the heart