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It binds poorly to IGF-binding proteins, which normally sequester IGF-1 in the body, allowing it to remain active and available for a significantly longer period

Overview of the rationale for l-glutamine treatment in moderate-severe COVID-19 infection

Walker RF, Codd EE, Barone FC, et al

Increased Protein Synthesis: By boosting protein synthesis, IGF-1 LR3 supports faster muscle repair and growth